Nausea and Vomiting Guidelines

The recommendations in these guidelines are adapted to the local context from the C17 endorsed Pediatric Oncology Group of Ontario (POGO) Guideline for the Prevention of Acute Nausea and Vomiting due to Antineoplastic Medication in Pediatric Cancer Patients, the POGO Guideline for Classification of the Acute Emetogenic Potential of Antineoplastic Medication in Pediatric Cancer Patients, and the POGO Guideline for the Prevention and Treatment of Anticipatory Nausea and Vomiting due to Chemotherapy in Pediatric Cancer Patients. The full versions of the guidelines which include the systematic reviews are available at: http://www.pogo.ca/healthcare/practiceguidelines
 
The APPHON/ROHPPA guideline utilized these systematic reviews and adapted the information for use in the Atlantic Provinces.  The APPHON/ROHPPA guideline provides   recommendations on the management of nausea and vomiting in children being treated for cancer or chemotherapy induced nausea and vomiting (CINV). The guideline will include the management of acute, delayed, anticipatory, breakthrough and refractory CINV. This guideline will also categorize antiemetic therapy based on the emetogenic potential of chemotherapy agents. The Pediatric Oncology Group of Ontario (POGO) has classified chemotherapy agents based on their emetogenic potential. This guideline will not include a review of alternative methods of nausea control, nor will it make recommendations, as it is felt the evidence in this area is not sufficient.
 
The supportive care guidelines have been adapted by appropriate Atlantic Provinces health professional specialists (physicians, pharmacists, nurses and other health professionals) using evidence-based or best practice references.  Format and content of the guidelines will change as they are reviewed and revised on a periodic basis.  Care has been taken to ensure accuracy of the information.  However, any physician or health professional using these guidelines will be responsible for verifying doses, and administering medications and care according to their own institutional formularies and policies and acceptable standards of care.